Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721052 | 0.85 | GPR119 (0.44) | GPR119FAAH | |
| SCHEMBL28870297 | 0.84 | GPR119 (0.50) | GPR119FAAH | |
| SCHEMBL1721381 | 0.84 | GPR119 (0.43) | GPR119FAAHPDE4B | |
| SCHEMBL611473 | 0.82 | GPR119 (0.42) | GPR119FAAH | |
| SCHEMBL13677270 | 0.81 | GPR119 (0.46) | GPR119FAAHPDE4B | |
| SCHEMBL865374 | 0.81 | ITGB3 (0.46) | GPR119FAAH | |
| SCHEMBL13676902 | 0.80 | GPR119 (0.45) | GPR119FAAH | |
| SCHEMBL4380554 | 0.80 | GPR119 (0.45) | GPR119FAAHPDE4B | |
| SCHEMBL11472234 | 0.78 | EPHX2 (0.39) | — | |
| SCHEMBL15219100 | 0.78 | GPR119 (0.67) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100764-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |