Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721381 | 0.87 | GPR119 (0.43) | GPR119FAAH | |
| SCHEMBL15835945 | 0.85 | GPR119 (0.46) | GPR119FAAH | |
| SCHEMBL1721777 | 0.85 | CHRNB2 (0.38) | GPR119FAAHP2RY12 | |
| SCHEMBL865374 | 0.85 | ITGB3 (0.46) | GPR119FAAH | |
| SCHEMBL28870297 | 0.81 | GPR119 (0.50) | GPR119FAAHMMP1MMP3MMP7 | |
| SCHEMBL611473 | 0.80 | GPR119 (0.42) | GPR119FAAH | |
| SCHEMBL4035282 | 0.79 | HPGD (0.48) | GPR119 | |
| SCHEMBL13677270 | 0.79 | GPR119 (0.46) | GPR119FAAH | |
| SCHEMBL26209372 | 0.78 | HRH3 (0.38) | — | |
| SCHEMBL13676902 | 0.78 | GPR119 (0.45) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406256-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103335-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |