Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865374 | 0.86 | ITGB3 (0.46) | GPR119CETPFAAHITGB3ITGA2B | |
| SCHEMBL13677270 | 0.86 | GPR119 (0.46) | GPR119CETPFAAHPDE4BITGB3 | |
| SCHEMBL13676902 | 0.85 | GPR119 (0.45) | GPR119CETPFAAH | |
| SCHEMBL28870297 | 0.83 | GPR119 (0.50) | GPR119FAAH | |
| SCHEMBL15835945 | 0.80 | GPR119 (0.46) | GPR119FAAHPDE4B | |
| SCHEMBL25092046 | 0.80 | GPR119 (0.42) | GPR119FAAHPDE4B | |
| SCHEMBL1721052 | 0.78 | GPR119 (0.44) | GPR119FAAH | |
| SCHEMBL15219100 | 0.77 | GPR119 (0.67) | GPR119FAAH | |
| SCHEMBL1721381 | 0.77 | GPR119 (0.43) | GPR119FAAHPDE4B | |
| SCHEMBL7986443 | 0.76 | GPR119 (0.43) | GPR119FAAHPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |