Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840464 | 0.88 | MMP8 (0.41) | MMP8FBP1CNR2CYP1A2CYP3A4 | |
| SCHEMBL20018408 | 0.86 | MMP8 (0.40) | MMP8FBP1CNR2CYP1A2CYP3A4 | |
| SCHEMBL15822495 | 0.83 | PPARG (0.32) | CNR2CYP1A2HPGDPPARAMEN1 | |
| SCHEMBL8434452 | 0.80 | MMP8 (0.52) | MMP8CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL15822482 | 0.76 | ALDH1A1 (0.35) | CYP1A2CYP3A4HPGDESR1PPARA | |
| SCHEMBL12713184 | 0.75 | TSHR (0.48) | MMP8FBP1CNR2CYP1A2CYP3A4 | |
| SCHEMBL11723700 | 0.75 | MEN1 (0.38) | MMP8FBP1CNR2CYP1A2CYP3A4 | |
| SCHEMBL11724728 | 0.75 | TSHR (0.39) | MMP8FBP1CNR2CYP1A2CYP3A4 | |
| SCHEMBL17257935 | 0.74 | PPARG (0.33) | HPGDPPARA | |
| SCHEMBL11863596 | 0.74 | HSD17B2 (0.44) | CNR2TSHRHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3301098-B1 | PROCESS FOR THE PREPARATION OF A LIGAND FOR A CATALYST | BOREALIS AG (AT) | 2020-02-19 | — | — | EP | disclosed |
| EP-3301098-A1 | PROCESS FOR THE PREPARATION OF A LIGAND FOR A CATALYST | Borealis AG (AT) | 2018-04-04 | — | — | EP | disclosed |
| EP-2935296-B1 | CATALYST | BOREALIS AG (AT) | 2017-11-15 | — | — | EP | disclosed |
| US-20150329653-A1 | CATALYST | BOREALIS AG (AT) | 2015-11-19 | — | — | US | disclosed |
| US-20150329653-A1 | CATALYST | BOREALIS AG (AT) | 2015-11-19 | — | — | US | disclosed |
| US-20150329653-A1 | CATALYST | BOREALIS AG (AT) | 2015-11-19 | — | — | US | disclosed |
| WO-2014096282-A1 | CATALYST | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |