Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17257934 | 0.87 | PKM (0.35) | HPGD | |
| SCHEMBL15822495 | 0.81 | PPARG (0.32) | PPARGPPARARIPK1HPGD | |
| SCHEMBL15822482 | 0.74 | ALDH1A1 (0.35) | PPARGPPARARIPK1HPGD | |
| SCHEMBL15840430 | 0.74 | MMP8 (0.40) | PPARAHPGD | |
| SCHEMBL20018381 | 0.74 | MAPT (0.36) | PPARGPPARAHPGD | |
| SCHEMBL15823061 | 0.73 | ELANE (0.45) | PPARGPPARA | |
| SCHEMBL23682722 | 0.69 | ALDH1A1 (0.38) | HPGD | |
| SCHEMBL15822946 | 0.68 | PKM (0.39) | — | |
| SCHEMBL15840459 | 0.66 | HPGD (0.53) | HPGD | |
| SCHEMBL28030624 | 0.65 | ALDH1A1 (0.37) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329653-A1 | CATALYST | BOREALIS AG (AT) | 2015-11-19 | — | — | US | disclosed |