Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840489 | 0.92 | NPC1 (0.57) | ALDH1A1POLBADAMTS5NPC1 | |
| SCHEMBL17208443 | 0.90 | ADAMTS5 (0.50) | ALDH1A1POLBADAMTS5SMN1; SMN2ESR1 | |
| SCHEMBL17208442 | 0.84 | ALDH1A1 (0.52) | ALDH1A1POLBADAMTS5SMN1; SMN2MAPK1 | |
| SCHEMBL15840440 | 0.82 | EPHX2 (0.48) | — | |
| SCHEMBL8902078 | 0.81 | ALDH1A1 (0.55) | ALDH1A1POLBADAMTS5SMN1; SMN2ESR1 | |
| SCHEMBL15840481 | 0.80 | EPHX2 (0.48) | — | |
| SCHEMBL8092824 | 0.80 | SIGMAR1 (0.59) | ALDH1A1POLBADAMTS5SMN1; SMN2MAPK1 | |
| SCHEMBL8901679 | 0.80 | ALDH1A1 (0.57) | ALDH1A1POLBADAMTS5SMN1; SMN2ESR1 | |
| SCHEMBL4198757 | 0.79 | NAMPT (0.65) | ALDH1A1POLBADAMTS5SMN1; SMN2ESR1 | |
| SCHEMBL15840447 | 0.78 | NPC1 (0.49) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| WO-2014096378-A1 | SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | NAT1, NAA15, FNTB | ALDH1A1 3861/4885POLB 586/4885ADAMTS5 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.