Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13774762 | 0.87 | CHRNA7 (0.51) | GAATSHRCHRNA7HTR3EHTR3B | |
| SCHEMBL16072769 | 0.79 | RAB9A (0.46) | GAATSHRKMT2A | |
| SCHEMBL16077039 | 0.79 | GAA (0.39) | GAATSHRAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL16077026 | 0.79 | RAB9A (0.46) | GAATSHRKMT2A | |
| SCHEMBL16072779 | 0.79 | GAA (0.39) | GAATSHRAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL16155139 | 0.79 | RAB9A (0.46) | GAATSHRKMT2A | |
| SCHEMBL4152261 | 0.75 | CHRNA7 (0.65) | GAATSHRCHRNA7HTR3EHTR3B | |
| SCHEMBL21570658 | 0.72 | ACACA (0.36) | KMT2AEPHX2 | |
| SCHEMBL21164349 | 0.72 | CHRNA7 (0.56) | GAATSHRCHRNA7HTR3EHTR3B | |
| SCHEMBL15382227 | 0.72 | CHRNA7 (0.57) | GAATSHRCHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |