SCHEMBL15842012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4108607	1.00	HTR5A (0.39)	HTR5AKCNA3CYP1A2CYP2D6CYP2C9
	SCHEMBL22627535	0.78	—	—
	SCHEMBL6244955	0.74	TAAR1 (0.35)	MEN1KMT2A
	SCHEMBL10509524	0.70	TDP1 (0.34)	CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4
	SCHEMBL10583695	0.70	TDP1 (0.34)	CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4
	SCHEMBL10585757	0.70	TDP1 (0.34)	CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4
	SCHEMBL4562954	0.68	C3AR1 (0.53)	HTR5AKCNA3CYP1A2CYP2D6CYP2C9
	SCHEMBL4562956	0.68	C3AR1 (0.53)	HTR5AKCNA3CYP1A2CYP2D6CYP2C9
	SCHEMBL3212571	0.67	MMP1 (0.40)	CYP1A2CYP2C19MEN1KMT2AGAA
	Octane SCHEMBL28084975	0.67	FKBP5 (0.67)	MMP2MMP9MMP3GPR84MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.