Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | UTRN | P46939 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621010 | 0.88 | NPC1 (0.54) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL18553033 | 0.86 | ALDH1A1 (0.58) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL18500358 | 0.84 | NPC1 (0.56) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL15845073 | 0.84 | RAB9A (0.58) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL4056655 | 0.84 | UTRN (0.56) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL15844590 | 0.83 | UTRN (0.56) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL30727501 | 0.82 | NPC1 (0.62) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL1913541 | 0.82 | NPC1 (0.62) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL2174585 | 0.82 | NPC1 (0.66) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL4059650 | 0.82 | VSIR (0.54) | NPC1ALDH1A1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-9246108-B2 | Quinoline-benzoxazole derived compounds for electronic films and devices | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-26 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
| CN-103915574-A | QUINOLINE-BENZOXAZOLE DERIVED COMPOUNDS FOR ELECTRONIC FILMS AND DEVICES | DOW GLOBAL TECHNOLOGIES LLC | 2014-07-09 | — | — | CN | disclosed |
| US-20140183413-A1 | QUINOLINE-BENZOXAZOLE DERIVED COMPOUNDS FOR ELECTRONIC FILMS AND DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | PAH, DDT, NISCH | NPC1 1346/4885ALDH1A1 1162/4885RAB9A 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.