Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849592 | 0.87 | CTSA (0.45) | RAB9ASMN1; SMN2CNR1HSD17B14CTSA | |
| SCHEMBL12468458 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ASMN1; SMN2KAT6A | |
| SCHEMBL3126732 | 0.87 | MCL1 (0.52) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL725121 | 0.84 | RAB9A (0.44) | MEN1KMT2ARAB9ASMN1; SMN2KAT6A | |
| SCHEMBL15849717 | 0.84 | HSD17B14 (0.57) | CNR2HSD17B14 | |
| SCHEMBL18157885 | 0.81 | TDP1 (0.52) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12467631 | 0.81 | CNR2 (0.54) | MEN1KMT2ARAB9ASMN1; SMN2CNR2 | |
| SCHEMBL4947900 | 0.80 | MEN1 (0.56) | MEN1KMT2ARAB9ASMN1; SMN2KAT6A | |
| SCHEMBL208097 | 0.80 | KDM4E (0.64) | MEN1KMT2ARAB9AKAT6ACNR2 | |
| SCHEMBL5109866 | 0.80 | HSD17B14 (0.60) | MEN1KMT2ARAB9AKAT6ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765667-B2 | HCV protease inhibitors | EISSENSTAT MICHAEL (US) | 2014-07-01 | — | — | US | disclosed |