SCHEMBL725121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15849615	0.84	MEN1 (0.50)	RAB9AMEN1KMT2AKAT6ACNR2
	SCHEMBL8374791	0.84	KDM4E (0.45)	RAB9AMEN1KMT2ATRPM8ALDH1A1
	SCHEMBL5309392	0.78	OXTR (0.46)	RAB9AMEN1KMT2ASMN1; SMN2
	SCHEMBL3739445	0.78	P2RX7 (0.49)	RAB9AMEN1KMT2AADORA3TRPM8
	SCHEMBL1260197	0.78	ALDH1A1 (0.52)	RAB9AMEN1KMT2AKAT6ACNR2
	SCHEMBL770109	0.77	KMO (0.60)	RAB9AKMT2AADORA3ALDH1A1SMN1; SMN2
	SCHEMBL306066	0.76	ALDH1A1 (0.41)	RAB9AMEN1KMT2ATRPM8CTSA
	SCHEMBL307224	0.76	GRM4 (0.46)	RAB9AMEN1KMT2ATRPM8CTSA
	SCHEMBL4088056	0.76	GRM5 (0.43)	MEN1KMT2ATRPM8CTSAALDH1A1
	SCHEMBL31546875	0.76	CTSA (0.40)	MEN1KMT2ATRPM8CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.