SCHEMBL15852425

SCHEMBL15852425

c1ccc(N(c2ccc3oc4ccccc4c3c2)c2cc3oc4ccc5ccccc5c4c3c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GLA P06280 2/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABCG2 Q9UNQ0 3/20 0.36
AHR P35869 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
FYN P06241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15852427 0.94 L3MBTL1 (0.39) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL15852949 0.94 MAPT (0.41) KDM4EHPGDMAPTL3MBTL1GLA
SCHEMBL24655092 0.93 KDM4E (0.38) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL22742400 0.92 MAPT (0.41) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL26342771 0.91 AHR (0.36) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL22739380 0.91 KDM4E (0.38) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL15852411 0.91 AHR (0.42) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL15852422 0.90 ABCG2 (0.38) KDM4EHPGDMAPTTDP1L3MBTL1
SCHEMBL25872824 0.90 MAPT (0.41) KDM4EHPGDMAPTL3MBTL1GLA
SCHEMBL15852098 0.90 KDM4E (0.34) KDM4EHPGDMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 US disclosed
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-11-09 US disclosed
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-11-09 US disclosed
US-9755156-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-09-05 US disclosed
US-9755156-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-09-05 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed
US-20140183500-A1 ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2014-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 KDM4E 256/4885HPGD 2977/4885MAPT 576/4885
US-20170324043-A1 OXYGEN-CONTAINING FUSED RING AMINE COMPOUND, SULFUR-CONTAINING FUSED RING AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SQOR, AOC1 KDM4E 256/4885HPGD 2977/4885MAPT 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.