Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | NPC1 | O15118 | 9/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | UBE2I | P63279 | 2/20 | 0.80 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.80 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.80 |
| ▸ | PKM | P14618 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.58 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024497 | 0.89 | KMT2A (1.00) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12319232 | 0.74 | KMT2A (1.00) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL18985299 | 0.71 | RAB9A (0.74) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL18985301 | 0.71 | RAB9A (0.74) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7669596 | 0.68 | JAK2 (0.60) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7002784 | 0.68 | JAK2 (0.60) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12319226 | 0.68 | KMT2A (0.84) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12319223 | 0.68 | KMT2A (0.84) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL13854028 | 0.66 | RAB9A (0.69) | RAB9AKMT2ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9767854 | 0.66 | RAB9A (0.69) | RAB9AKMT2ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140187444-A1 | METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING O-GLYCOSYLATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-03 | — | — | US | disclosed |