Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586363 | 0.88 | EGLN1 (0.50) | EGLN3EGLN1HIF1AEGLN2MAPT | |
| SCHEMBL1585687 | 0.86 | EGLN1 (0.56) | EGLN3EGLN1EGLN2 | |
| SCHEMBL1585836 | 0.84 | EGLN1 (0.48) | EGLN3EGLN1HIF1AEGLN2TP53 | |
| SCHEMBL1585869 | 0.84 | EGLN1 (0.47) | EGLN3EGLN1HIF1AEGLN2LMNA | |
| SCHEMBL1585642 | 0.83 | EGLN1 (0.50) | EGLN3EGLN1EGLN2 | |
| SCHEMBL1586373 | 0.82 | EGLN3 (0.45) | EGLN3EGLN1HIF1ATP53MAPT | |
| SCHEMBL1586489 | 0.81 | EGLN1 (0.45) | EGLN3EGLN1EGLN2 | |
| SCHEMBL1585822 | 0.81 | EGLN1 (0.47) | EGLN3EGLN1HIF1ALMNAMAPT | |
| SCHEMBL1585825 | 0.81 | EGLN1 (0.48) | EGLN3EGLN1POLBTSHR | |
| SCHEMBL1585982 | 0.80 | ALDH1A1 (0.46) | EGLN3EGLN1EGLN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |