Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 11/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 9/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585836 | 0.89 | EGLN1 (0.48) | EGLN1EGLN3EGLN2TDP1BBOX1 | |
| SCHEMBL1585869 | 0.86 | EGLN1 (0.47) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585761 | 0.86 | EGLN1 (0.53) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL1585687 | 0.85 | EGLN1 (0.56) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585822 | 0.82 | EGLN1 (0.47) | EGLN1EGLN3BBOX1ASPHKDM8 | |
| SCHEMBL1585642 | 0.81 | EGLN1 (0.50) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1586363 | 0.81 | EGLN1 (0.50) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585880 | 0.81 | EGLN3 (0.46) | EGLN1EGLN3EGLN2 | |
| SCHEMBL1585982 | 0.81 | ALDH1A1 (0.46) | EGLN1EGLN3EGLN2BBOX1ASPH | |
| SCHEMBL1969923 | 0.81 | EGLN1 (0.48) | EGLN1EGLN3EGLN2CYSLTR2BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |