SCHEMBL1586597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1586593	1.00	AR (0.53)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL6228324	0.89	AR (0.61)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL8811629	0.83	AR (0.56)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL5010945	0.83	AR (0.56)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL34468026	0.82	SMN1; SMN2 (0.53)	TSHRMAPTLMNAPOLBNPSR1
	SCHEMBL20314692	0.82	AR (0.54)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL6746278	0.82	AR (0.54)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL11247517	0.82	PTGS1 (0.59)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL43535	0.82	PTGS1 (0.59)	ARTSHRMAPK1MAPTLMNA
	SCHEMBL21194	0.80	CYP1A2 (0.60)	ARTSHRMAPK1CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.