Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KIF20A | O95235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869816 | 0.96 | CRHBP (0.46) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15869765 | 0.93 | CRHBP (0.44) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15869788 | 0.91 | TDP1 (0.36) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15862454 | 0.89 | MAPT (0.45) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15862453 | 0.89 | MAPT (0.45) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL14722523 | 0.87 | POLB (0.50) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL14722525 | 0.87 | POLB (0.50) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15869798 | 0.86 | KIF20A (0.42) | CRHBPCRHR2ALDH1A1HPGDPOLB | |
| SCHEMBL15862388 | 0.86 | CRHBP (0.46) | CRHBPCRHR2ALDH1A1HPGDTDP1 | |
| SCHEMBL15862389 | 0.86 | CRHBP (0.46) | CRHBPCRHR2ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | CRHBP 3646/4885CRHR2 4262/4885ALDH1A1 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.