Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 4/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 4/20 | 1.00 |
| ▸ | CYP2E1 | P05181 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590048 | 1.00 | CYP2A6 (1.00) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL19219088 | 0.92 | CYP2A6 (0.85) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL9192615 | 0.87 | CYP2A6 (0.76) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL28373020 | 0.86 | CYP2A6 (0.74) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| Pyridine SCHEMBL30984530 | 0.83 | CYP3A4 (0.70) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL28511535 | 0.82 | CYP2A6 (0.69) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL23004809 | 0.82 | CYP2E1 (0.69) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL9058679 | 0.81 | RAB9A (1.00) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL1357023 | 0.80 | CYP2A6 (0.67) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 | |
| SCHEMBL18789395 | 0.80 | CYP3A4 (0.67) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486854-A | One-pot method for preparing 2, 5-diaryl substituted thiophene | 浙江大学 | 2024-02-02 | — | — | CN | claimed |
| CN-106391122-A | A synthetic method of a polypyrrole-functionalized cobalt complex composite material and applications of the material | 渤海大学 | 2017-02-15 | — | — | CN | claimed |
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2008-08-07 | — | — | US | claimed |
| CN-1733759-A | Oligomerized thiofuran ligand and its complex with rare earth, and their preparation method | UNIV SOUTH CHINA TECH (CN) | 2006-02-15 | — | — | CN | claimed |
| WO-2005066162-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2005-07-21 | — | — | WO | claimed |
| CN-121800769-A | Synthesis method of 2-aryl-5-alkyl-3-pyridylthiophene | 广西大学 | 2026-04-07 | — | — | CN | disclosed |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | NIPPON SHINYAKU CO., LTD. (JP) | 2025-12-30 | — | — | US | disclosed |
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-111527094-B | Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2024-03-26 | — | — | CN | disclosed |
| CN-117486854-A | One-pot method for preparing 2, 5-diaryl substituted thiophene | 浙江大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117137909-A | Application of indenopyrrole derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-111212844-B | Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2023-08-25 | — | — | CN | disclosed |
| EP-0894088-A1 | SUBSTITUTED SULFONIC ACID N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998025611-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| WO-1998024784-A1 | SUBSTITUTED SULFONIC ACID N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4723988-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4684393-A | PLATN GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | CYP2A13, CYP2A6, CYP2B6 | CYP2A6 2/4885CYP3A4 45/4885CYP2C9 44/4885 |
| US-12509424-B2 | Compound and composition as PDGF receptor kinase inhibitor | PDGFRA, PDGFRB, PDGFA | CYP2A6 3817/4885CYP3A4 4446/4885CYP2C9 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.