SCHEMBL15875871

SCHEMBL15875871

CC(C)(C)c1ccc(Nc2ccccc2N)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.65
GAA P10253 5/20 0.65
TDP1 Q9NUW8 2/20 0.65
KDM4E B2RXH2 4/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
TP53 P04637 1/20 0.63
APP P05067 1/20 0.63
HPGD P15428 1/20 0.63
ALOX15 P16050 1/20 0.63
SNCA P37840 1/20 0.63
BLM P54132 1/20 0.63
HSD17B10 Q99714 1/20 0.63
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
LMNA P02545 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30323778 1.00 MAPT (0.65) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL6656632 0.88 MAPK13 (0.73) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL17546531 0.86 AKR1C3 (0.45) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL4607773 0.84 MAPT (0.86) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL24988399 0.84 MAPT (0.57) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL29824523 0.81 MAPT (0.68) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL15875869 0.81 MAPT (0.68) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL9703296 0.79 P2RY1 (0.42) MAPTGAATDP1KDM4ESMN1; SMN2
SCHEMBL4901952 0.79 P2RX7 (0.46) MAPTGAATDP1SMN1; SMN2TP53
SCHEMBL6290887 0.79 MAPT (0.59) MAPTGAATDP1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230118772-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
CN-107011268-B The 1,3,6,8- tetra- of bipolarity D- π-A configuration replaces pyrenyl material and preparation method and application 中国矿业大学 2019-07-23 CN disclosed
CN-106905242-B The two poles of the earth configuration pyrenyl containing benzimidazole unit blue light material and preparation method and application 中国矿业大学 2019-07-12 CN disclosed
CN-107011268-A The 1,3,6,8 4 substitution pyrenyl materials and preparation method and application of bipolarity D π A configurations 中国矿业大学 2017-08-04 CN disclosed
CN-106905242-A The two poles of the earth configuration pyrenyl containing benzimidazole unit blue light material and preparation method and application 中国矿业大学 2017-06-30 CN disclosed
US-8785002-B1 High-energy triplet host materials, luminescent layer comprising the same, and organic electroluminescent device comprising the luminescent layer BOWLING GREEN STATE UNIVERSITY (US) 2014-07-22 US disclosed
US-8785002-B1 High-energy triplet host materials, luminescent layer comprising the same, and organic electroluminescent device comprising the luminescent layer BOWLING GREEN STATE UNIVERSITY (US) 2014-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118772-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, LIG1, AP1M1 MAPT 1261/4885GAA 2695/4885TDP1 3068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.