Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789693 | 0.71 | CHRM1 (0.33) | — | |
| SCHEMBL1587116 | 0.70 | ALDH1A1 (0.58) | TDP1ALDH1A1TSHRCYP3A4GLA | |
| SCHEMBL1588109 | 0.70 | ALDH1A1 (0.58) | TDP1ALDH1A1TSHRCYP3A4GLA | |
| SCHEMBL8788276 | 0.70 | — | — | |
| SCHEMBL10369462 | 0.69 | TDP1 (0.34) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL9167426 | 0.69 | TDP1 (0.36) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL7975046 | 0.67 | ALDH1A1 (0.56) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL11150188 | 0.66 | TDP1 (0.47) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL10982331 | 0.65 | TDP1 (0.45) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL4308247 | 0.64 | TDP1 (0.41) | TDP1ALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | SYN-TECH CHEM. & PHARM. CO., LTD. (TW) | 2011-04-21 | — | — | US | disclosed |
| EP-0591486-A1 | IMMUNO-ACTIVATING AND HENCE ANTI-VIRAL EFFECT OF 4- 3-(SUBST.-AMINO)-2-HYDROXYPROPOXY]-1,2,5-THIADIAZOLE COMPOUNDS | PEUSCHEL, Karin, Elisabeth (CH) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993020814-A1 | IMMUNO-ACTIVATING AND HENCE ANTI-VIRAL EFFECT OF 4-[3-(SUBST.-AMINO)-2-HYDROXYPROPOXY]-1,2,5-THIADIAZOLE COMPOUNDS | PEUSCHEL KARIN ELISABETH (CH) | 1993-10-28 | — | — | WO | disclosed |
| US-4634713-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0096006-A2 | 3-(Ureidocyclohexylamino)-propane-1,2-diol derivatives, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | KCNH3, KCNN3, KCNH2 | TDP1 2302/4885ALDH1A1 1588/4885TSHR 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.