SCHEMBL158783

SCHEMBL158783

COC(=O)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
FPR2 P25090 2/20 0.45
SCN9A Q15858 2/20 0.45
IDH1 O75874 1/20 0.44
MAPK14 Q16539 1/20 0.43
LMNA P02545 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
ALDH2 P05091 1/20 0.42
MMP2 P08253 4/20 0.42
MMP9 P14780 4/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
MMP3 P08254 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11484702 0.95 KMT2A (0.48) MEN1MAPTKMT2AL3MBTL1IDH1
SCHEMBL25576006 0.95 KMT2A (0.48) MEN1MAPTKMT2AL3MBTL1IDH1
SCHEMBL30469158 0.95 KMT2A (0.48) MEN1MAPTKMT2AL3MBTL1IDH1
SCHEMBL10430361 0.89 FPR2 (0.42) MEN1MAPTKMT2AL3MBTL1FPR2
SCHEMBL11347546 0.88 FPR2 (0.42) MEN1MAPTKMT2AL3MBTL1FPR2
SCHEMBL21991246 0.87 FPR2 (0.44) MEN1MAPTKMT2AFPR2SCN9A
SCHEMBL11155690 0.86 MAPT (0.41) MEN1MAPTKMT2AL3MBTL1IDH1
SCHEMBL403443 0.85 IDH1 (0.55) MEN1KMT2AL3MBTL1FPR2SCN9A
SCHEMBL21991874 0.85 MAPK14 (0.41) MAPTFPR2SCN9AMAPK14LMNA
SCHEMBL11006160 0.85 FPR2 (0.40) MEN1MAPTKMT2AL3MBTL1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 992 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2021-12-09 US claimed
EP-3174865-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-12-09 EP claimed
WO-2020154349-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS BAYER CROPSCIENCE LP (US) 2020-07-30 WO claimed
US-20200236925-A1 METHODS AND FORMULATIONS FOR PREVENTING DOWNWARD MIGRATION OF AGRICULTURAL MATERIALS DISCOVERY PURCHASER CORPORATION 2020-07-30 US claimed
US-RE48057-E1 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2020-06-23 US claimed
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-02-20 US claimed
EP-3145312-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2019-11-20 EP claimed
EP-3160943-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-09-18 EP claimed
US-20120283099-A1 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-08 US claimed
US-20120283100-A1 CONTROLLING PLANTHOPPERS DOW AGROSCIENCES LLC (US) 2012-11-08 US claimed
WO-2012103393-A2 CONTROLLING MEALYBUGS DOW AGROSCIENCES LLC (US) 2012-08-02 WO claimed
US-20120195974-A1 CONTROLLING MEALYBUGS DOW AGROSCIENCES LLC (US) 2012-08-02 US claimed
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto CORTEVA AGRISCIENCE LLC 2012-05-03 US claimed
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-03 US claimed
EP-0330904-B1 Herbicidal agent in the form of aqueous microemulsions HOECHST AG (DE) 1994-04-20 EP claimed
US-4973352-A Herbicidal agents in the form of aqueous transparent microemulsions HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-27 US claimed
US-4380661-A HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1983-04-19 US claimed
EP-0025079-A1 Optically active D-isomers of propionic acid derivatives, herbicides containing them, use of those derivatives and herbicidal product for combating weeds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-03-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT MEN1 4740/4885MAPT 1128/4885KMT2A 1602/4885
US-20210378241-A1 COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, GAP43, PDHA2 MEN1 4629/4885MAPT 1771/4885KMT2A 2371/4885
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, AGPS, DDT MEN1 2951/4885MAPT 3668/4885KMT2A 3634/4885
US-20200055846-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS MEN1 2610/4885MAPT 3415/4885KMT2A 3565/4885
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto ACHE, DDT, PTMS MEN1 2610/4885MAPT 3415/4885KMT2A 3565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.