SCHEMBL994122

SCHEMBL994122

Cc1cc(O)c(-c2c(O)cc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
G6PD P11413 1/20 0.43
CYP2C9 P11712 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
CCR6 P51684 1/20 0.43
HIF1A Q16665 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274830 0.81 PDE4B (0.44) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL1245515 0.81 TDP1 (0.39) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL3680700 0.80 MAPT (0.56) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL30058203 0.80 MAPT (0.56) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL10785880 0.79 MAPT (0.39) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL162989 0.79 KDM4E (0.37) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL393790 0.79 ACHE (0.50) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL31305641 0.79 ACHE (0.50) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL2026441 0.77 ACHE (0.48) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL2912790 0.77 SELL (0.48) MAPTKDM4EMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508056-B1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-06 EP disclosed
US-20250257088-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-14 US disclosed
US-20250250291-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH ALDEHYDE FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-07 US disclosed
EP-4508056-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
EP-4508055-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH ALDEHYDE FUNCTIONALITY Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
WO-2023200935-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
WO-2023200934-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH ALDEHYDE FUNCTIONALITY DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
EP-1905511-B1 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA TECH SARL (CH) 2013-03-27 EP disclosed
EP-2277623-A2 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2011-01-26 EP disclosed
EP-1448298-B1 POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS INVISTA TECH SARL (CH) 2010-09-22 EP disclosed
US-20040054105-A1 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INV NYLON CHEMICALS AMERICAS, LLC 2004-03-18 US disclosed
US-6660876-B2 Ethylenically unsaturated, phosphorus-containing, bidentate ligands E. I. DU PONT DE NEMOURS AND COMPANY 2003-12-09 US disclosed
US-20030144440-A1 Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INV NYLON CHEMICALS AMERICAS, LLC 2003-07-31 US disclosed
WO-2003045883-A1 PROCESS FOR PREPARING 3,3',5,5',6,6'-HEXAALKYL-2,2'-BIPHENOLS, 3,3',4,4',5,5'-HEXAALKYL-2,2'-BIPHENOLS AND 3,3',4,4',5,5',6,6'-OCTAALKYL-2,2'-BIPHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-06-05 WO disclosed
WO-2003045552-A2 POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-06-05 WO disclosed
EP-0684249-B1 Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes TAKASAGO PERFUMERY CO LTD (JP) 2003-02-19 EP disclosed
EP-0684230-B1 4- (R)-1'-formylethyl azetidin-2-one derivatives TAKASAGO PERFUMERY CO LTD (JP) 2002-07-03 EP disclosed
US-6025503-A REACTING OPTICALLY ACTIVE(OR RACEMIC) TITANIUM ALKOXIDE COMPLEXES WITH CHIRAL ACTIVATORS(ESPECIALLY DIOLS) YIELDS NEW TITANIUM COMPLEXES WHICH ARE ENANTIO-SELECTIVE IN C-C BOND FORMING REACTIONS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-02-15 US disclosed
EP-0684249-A1 Phosphine compounds, complexes containing the phosphine compounds as ligands, and process for producing optically active aldehydes using the phosphine compounds or complexes Takasago International Corporation (JP) 1995-11-29 EP disclosed
EP-0684230-A1 4- (R)-1'-formylethyl azetidin-2-one derivatives Takasago International Corporation (JP) 1995-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250291-A1 PREPARATION OF ORGANOSILICON COMPOUNDS WITH ALDEHYDE FUNCTIONALITY HVCN1, ALDH16A1, ALDH3A1 MAPT 4327/4885KDM4E 1612/4885MEN1 2253/4885
US-20250257088-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX PPIP5K2, INPP5B, PIP4K2B MAPT 3189/4885KDM4E 3702/4885MEN1 187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.