SCHEMBL162989

SCHEMBL162989

Cc1cc(O)c(-c2c(O)c(C)c(Br)c(Br)c2Br)c(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
RECQL P46063 1/20 0.35
ACLY P53396 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
G6PD P11413 1/20 0.30
CYP2C9 P11712 1/20 0.30
PKM P14618 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
CYP2C19 P33261 1/20 0.30
CCR6 P51684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994122 0.79 MAPT (0.46) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL158804 0.77 MGAM (0.35) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL31088765 0.71 ALDH1A1 (0.40) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL7173958 0.71 ALDH1A1 (0.40) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL10785880 0.70 MAPT (0.39) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL10758757 0.70 ALDH1A1 (0.36) ALDH1A1HPGDRECQLCYP1A2CYP3A4
SCHEMBL86951 0.69 CA1 (0.42) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL3123767 0.69 PTPN1 (0.44) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL3680700 0.68 MAPT (0.56) KDM4EMAPTMEN1KMT2AUSP2
SCHEMBL30058203 0.68 MAPT (0.56) KDM4EMAPTMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794713-B1 TOUGHENING AGENT FOR EPOXY THERMOSET DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-06 EP claimed
US-9657118-B2 Toughening agent for epoxy thermoset DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-23 US claimed
WO-2017030754-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-23 WO claimed
WO-2017027201-A1 EPOXY MATERIALS WITH IMPROVED PROCESSABILITY AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027199-A1 EPOXY MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017027200-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-16 WO claimed
WO-2017019677-A1 EPOXY THERMOSET MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
WO-2017019679-A1 EPOXY MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 WO claimed
US-9006385-B2 Elastomeric epoxy materials and the use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-14 US claimed
EP-2611849-B1 ELASTOMERIC INSULATION MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-03-18 EP claimed
WO-2012030339-A1 ELASTOMERIC INSULATION MATERIALS AND THE USE THEREOF IN SUBSEA APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-08 WO claimed
WO-2012030338-A1 ELASTOMERIC EPOXY MATERIALS AND THE USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-08 WO claimed
US-7592067-B2 Epoxy resin compositions, processes utilizing same and articles made therefrom HEXION SPECIALTY CHEMICALS, INC. (US) 2009-09-22 US claimed
US-20060217516-A1 Tertiary amine modified polyurethane products made therefrom CASATI FRANCOIS M 2006-09-28 US claimed
US-20060052570-A1 Amine-epoxy autocatalytic polymers and polyurethane products made therefrom GAN JOSEPH 2006-03-09 US claimed
EP-1470174-A1 TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-10-27 EP claimed
WO-2003055930-A1 TERTIARY AMINE MODIFIED POLYOLS AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-07-10 WO claimed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US claimed
US-4725652-A TETRASUBSTITUTED ONIUM COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1988-02-16 US claimed
US-4665149-A Triazine containing epoxy resins having improved thermal stability THE DOW CHEMICAL COMPANY (US) 1987-05-12 US claimed