SCHEMBL15899192

SCHEMBL15899192

COCOCc1cn(CC2(CO)COC(C)(C)OC2)c([N+](=O)[O-])n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MITF O75030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14822360 0.82 MEN1 (0.32) —
SCHEMBL15899193 0.81 MITF (0.32) MITF
SCHEMBL15899177 0.81 SMYD2 (0.32) —
SCHEMBL14822595 0.72 LMNA (0.43) —
SCHEMBL15899150 0.69 SMYD2 (0.34) —
SCHEMBL14822359 0.66 — —
SCHEMBL15899355 0.65 CA12 (0.44) —
SCHEMBL15899135 0.65 — —
SCHEMBL18633545 0.63 KCNA4 (0.32) —
SCHEMBL15899147 0.63 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759538-B1 RADIOACTIVE FLUORINE LABELED COMPOUND NIHON MEDIPHYSICS CO LTD (JP) 2016-03-23 — — EP disclosed
US-9107964-B2 Radioactive fluorine-labeled compound NIHON MEDI-PHYSICS CO., LTD. (JP) 2015-08-18 — — US disclosed
US-20140364620-A1 RADIOACTIVE FLUORINE-LABELED COMPOUND NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2014-12-11 — — US disclosed
EP-2759538-A1 RADIOACTIVE FLUORINE LABELED COMPOUND Nihon Medi-Physics Co., Ltd. (JP) 2014-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364620-A1 RADIOACTIVE FLUORINE-LABELED COMPOUND AFF1, PRMT1, DOT1L MITF 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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