⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822360 | 0.85 | MEN1 (0.32) | — | |
| SCHEMBL15899193 | 0.82 | MITF (0.32) | — | |
| SCHEMBL14822353 | 0.81 | CA12 (0.39) | — | |
| SCHEMBL15899140 | 0.75 | CA12 (0.41) | — | |
| SCHEMBL10047554 | 0.74 | STAT3 (0.37) | — | |
| SCHEMBL10015860 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL18589129 | 0.72 | CA12 (0.38) | — | |
| SCHEMBL18633388 | 0.70 | CA12 (0.39) | — | |
| SCHEMBL10015859 | 0.68 | KMT2A (0.39) | — | |
| SCHEMBL31722148 | 0.66 | STAT3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759538-B1 | RADIOACTIVE FLUORINE LABELED COMPOUND | NIHON MEDIPHYSICS CO LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-9107964-B2 | Radioactive fluorine-labeled compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140364620-A1 | RADIOACTIVE FLUORINE-LABELED COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2014-12-11 | — | — | US | disclosed |
| EP-2759538-A1 | RADIOACTIVE FLUORINE LABELED COMPOUND | Nihon Medi-Physics Co., Ltd. (JP) | 2014-07-30 | — | — | EP | disclosed |