Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661183 | 0.98 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL10786977 | 0.82 | CHRM2 (0.47) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL1802466 | 0.79 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL43427 | 0.79 | MAPK1 (0.58) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL9507123 | 0.77 | TSHR (0.48) | ALDH1A1ACHECYP2C19KIF11CYP3A4 | |
| SCHEMBL3317801 | 0.77 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL29090083 | 0.77 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL2350021 | 0.76 | KIF11 (0.56) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL379267 | 0.76 | KCNN4 (0.43) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL7053535 | 0.76 | KCNN4 (0.43) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351730-B1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | SHANGHAI ECUST BIOMEDICINE CO LTD (CN) | 2014-07-30 | — | — | EP | claimed |