SCHEMBL43427

SCHEMBL43427

CCOC(C)(C)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.58
ALDH1A1 P00352 2/20 0.54
ALOX15 P16050 1/20 0.54
TAAR1 Q96RJ0 1/20 0.43
KCNN4 O15554 3/20 0.41
KIF11 P52732 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 1/20 0.36
POLB P06746 1/20 0.36
LTA4H P09960 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
CASR P41180 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2816581 0.87 MAPK1 (0.40) MAPK1ALDH1A1ALOX15ESR1ESR2
Di(Hydroxyethyl)Ether SCHEMBL28094468 0.85 ALDH1A1 (0.46) MAPK1ALDH1A1ALOX15KIF11CYP2C19
SCHEMBL1224411 0.84 MAPK1 (0.56) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL9470984 0.83 MAPK1 (0.61) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL1802466 0.81 MAPK1 (0.46) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL661183 0.81 MAPK1 (0.46) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL19144067 0.81 ESR1 (0.42) MAPK1ALDH1A1ALOX15HIF1AESR1
SCHEMBL10534242 0.79 TSHR (0.48) MAPK1ALDH1A1ALOX15KIF11MAPT
Ammonia Solution, Strong SCHEMBL15899765 0.79 MAPK1 (0.44) MAPK1ALDH1A1ALOX15TAAR1KCNN4
SCHEMBL9226771 0.79 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP claimed
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-20130150539-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-06-13 US claimed
US-8394897-B2 Production of vinylidene-terminated polyolefins via quenching with monosulfides CHEVRON ORONITE COMPANY LLC (US) 2013-03-12 US claimed
US-8383736-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-02-26 US claimed
US-8362153-B2 Have improved low temperature and high temperature viscometric properties; sulfonating polyisobutene and reacting the polyisobutenyl sulfonate with an alkali metal or alkaline earth metal CHEVRON ORONITE COMPANY LLC (US) 2013-01-29 US claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
EP-1781715-B1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2011-05-18 EP claimed
EP-1803748-A1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1786843-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS Chevron Oronite Company LLC (US) 2007-05-23 EP claimed
EP-1781715-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS Chevron Oronite Company LLC (US) 2007-05-09 EP claimed
WO-2006023742-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC (US) 2006-03-02 WO claimed
WO-2006023988-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC (US) 2006-03-02 WO claimed
US-20060041084-A1 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC 2006-02-23 US claimed
US-20060041083-A1 quenching cationic quasi-living polyolefin polymer system with pyrroles, imidazoles; lubricating oil additives CHEVRON ORONITE COMPANY LLC 2006-02-23 US claimed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US claimed
US-20040260033-A1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI 2004-12-23 US claimed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP claimed