Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL15899765 | 0.98 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL10786977 | 0.84 | CHRM2 (0.47) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL1802466 | 0.81 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL43427 | 0.81 | MAPK1 (0.58) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL29090083 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL3317801 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15CHRM2 | |
| SCHEMBL9507123 | 0.79 | TSHR (0.48) | ALDH1A1ACHECYP2C19KIF11CYP3A4 | |
| SCHEMBL2350021 | 0.78 | KIF11 (0.56) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL379267 | 0.78 | KCNN4 (0.43) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 | |
| SCHEMBL7053535 | 0.78 | KCNN4 (0.43) | MAPK1ALDH1A1TAAR1ALOX15KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351730-B1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | SHANGHAI ECUST BIOMEDICINE CO LTD (CN) | 2014-07-30 | — | — | EP | claimed |
| CN-102245560-B | Ethoxy diphenyl ethane derivates, preparation processes and uses thereof | SHANGHAI ECUST BIOMEDICINE CO LTD | 2014-04-16 | — | — | CN | claimed |
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | Zhejiang Wild Wind Pharmaceutical Co., Ltd. (CN) | 2012-02-23 | — | — | US | claimed |
| CN-102245560-A | Ethoxy diphenyl ethane derivates, preparation processes and uses thereof | SHANGHAI ECUST BIOMEDICINE CO | 2011-11-16 | — | — | CN | claimed |
| EP-2351730-A1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | Shanghai Ecust Biomedicine Co., Ltd (CN) | 2011-08-03 | — | — | EP | claimed |
| CN-101723813-A | Ethoxy diphenyl ethane derivative and preparation method and application thereof | SHANGHAI ECUST BIOMEDICINE CO | 2010-06-09 | — | — | CN | claimed |
| CN-119390572-A | Dichloroacetic acid coupling diphenyl ethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| US-20240350448-A1 | DICHLOROACETIC ACID CONJUGATING DIPHENYL ETHANE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI ECUSTBIOMEDICINECOMPANY LTD. (CN) | 2024-10-24 | — | — | US | disclosed |
| CN-114230466-B | Dichloroacetic acid coupling diphenyl ethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2023123695-A1 | DICHLOROACETIC-ACID-COUPLED DIPHENYLETHANE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华理生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-107311846-B | Gem difluoroethyl substituted stilbene and diphenylethane derivatives, and preparation method and application thereof | 上海华理生物医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114230466-A | Dichloroacetic acid coupled diphenylethane compound, preparation method and application thereof | 上海华理生物医药股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-11279678-B2 | 5-fluorouracil derivatives, preparation methods and uses thereof | SHANGHAI ECUST BIOMEDICINE CO., LTD. (CN) | 2022-03-22 | — | — | US | disclosed |
| CN-100391963-C | Process for preparing C-aryl glucoside SGLT2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2008-06-04 | — | — | CN | disclosed |
| CN-1756759-A | Process for preparing C-aryl glucoside SGLT2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2006-04-05 | — | — | CN | disclosed |
| EP-0261962-B1 | PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0197311-B1 | PROCESS FOR POLYMERIZING ETHYLENE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| US-4762898-A | Process for polymerizing ethylene | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0261962-A2 | Process for producing propylene block copolymer | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |
| EP-0197311-A2 | Process for polymerizing ethylene | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1986-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240350448-A1 | DICHLOROACETIC ACID CONJUGATING DIPHENYL ETHANE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | DDT, DDC, PCCA | MAPK1 2581/4885ALDH1A1 143/4885TAAR1 2770/4885 |
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | TUBB1, TUBB, TUBB3 | MAPK1 1176/4885ALDH1A1 1714/4885TAAR1 1915/4885 |
| US-11279678-B2 | 5-fluorouracil derivatives, preparation methods and uses thereof | VEGFA, FLT4, FAU | MAPK1 3579/4885ALDH1A1 566/4885TAAR1 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.