Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790774 | 0.89 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL7989269 | 0.88 | LMNA (0.83) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL1045922 | 0.88 | LMNA (0.83) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL7989530 | 0.88 | LMNA (0.83) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL11356824 | 0.88 | LMNA (0.83) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL22802252 | 0.87 | ALDH1A1 (0.66) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL26229511 | 0.86 | HRH3 (0.72) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL22802254 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10502877 | 0.85 | LMNA (0.67) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL15901736 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192578-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2020251969-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |