Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28327016 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2CA2 | |
| Benzene SCHEMBL28326432 | 0.82 | CES1 (0.53) | CYP3A4TDP1ESR1CA2CA4 | |
| SCHEMBL5028587 | 0.82 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2CA2 | |
| SCHEMBL67982 | 0.82 | CES1 (0.53) | CYP3A4TDP1ESR1CA2CA4 | |
| Benzene SCHEMBL6890099 | 0.82 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2CA2 | |
| SCHEMBL2085135 | 0.82 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2CA2 | |
| SCHEMBL101 | 0.82 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2CA2 | |
| SCHEMBL31544056 | 0.79 | TDP1 (0.80) | CYP3A4TDP1ESR1ESR2CA2 | |
| Methyl Alcohol SCHEMBL16974123 | 0.79 | TDP1 (0.80) | CYP3A4TDP1ESR1ESR2CA2 | |
| SCHEMBL25384985 | 0.78 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315465-B2 | Photostable AIE luminogens for specific mitochondrial imaging and its method of manufacturing thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-19 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140212359-A1 | PHOTOSTABLE AIE LUMINOGENS FOR SPECIFIC MITOCHONDRIAL IMAGING AND ITS METHOD OF MANUFACTURING THEREOF | MAVS, AIFM1, GSR | CYP3A4 2123/4885TDP1 756/4885ESR1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.