Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904212 | 1.00 | CA2 (0.51) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL15904691 | 0.96 | TDP1 (0.54) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL15904256 | 0.85 | CA2 (0.51) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL15904255 | 0.85 | CA2 (0.51) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL10658071 | 0.84 | CA2 (0.58) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL10658082 | 0.84 | CA2 (0.58) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL17313720 | 0.84 | MMP2 (0.46) | TDP1L3MBTL1 | |
| SCHEMBL15904014 | 0.84 | MMP2 (0.46) | TDP1L3MBTL1 | |
| SCHEMBL15903711 | 0.83 | TDP1 (0.52) | CA2ALDH1A1TDP1L3MBTL1NPSR1 | |
| SCHEMBL17313813 | 0.83 | CNR2 (0.43) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | CA2 209/4885ALDH1A1 289/4885TDP1 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.