Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749701 | 0.88 | CYP3A4 (0.56) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL7978731 | 0.86 | PTPN7 (0.66) | ALDH1A1HTTALOX15MEN1KMT2A | |
| SCHEMBL3171559 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HTTALOX15MEN1KMT2A | |
| SCHEMBL30439679 | 0.80 | PTPN7 (0.71) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL1478177 | 0.80 | PTPN7 (0.71) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL14816245 | 0.80 | KDM4E (0.60) | ALDH1A1HTTALOX15MAPTHSD17B10 | |
| SCHEMBL6802001 | 0.80 | RAB9A (0.50) | MEN1KMT2APOLBPTPN7TSHR | |
| SCHEMBL27680141 | 0.79 | AGXT (0.61) | ALDH1A1HTTALOX15MEN1KMT2A | |
| SCHEMBL27657434 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HTTALOX15MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27898425 | 0.78 | AGXT (0.62) | ALDH1A1HTTALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | FMC CORP (US) | 2018-11-01 | — | — | US | disclosed |
| US-10015966-B2 | Fungicidal pyrazole mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| EP-2809157-B1 | FUNGICIDAL PYRAZOLE MIXTURES | DU PONT (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| WO-2015157005-A1 | SUBSTITUTED TOLYL FUNGICIDE MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-15 | — | — | WO | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2809157-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. Du Pont de Nemours and Company (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2014130409-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2013126283-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013116251-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ALDH1A1 1167/4885HTT 3798/4885ALOX15 923/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ALDH1A1 1167/4885HTT 3798/4885ALOX15 923/4885 |
| US-10015966-B2 | Fungicidal pyrazole mixtures | CYP1B1, CBR3, CBR1 | ALDH1A1 526/4885HTT 3725/4885ALOX15 581/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | ALDH1A1 1167/4885HTT 3798/4885ALOX15 923/4885 |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | CYP1B1, CBR3, CBR1 | ALDH1A1 526/4885HTT 3725/4885ALOX15 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.