Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086744 | 0.67 | MEN1 (0.41) | NFKB1MEN1KMT2ACES2CES1 | |
| Toluene SCHEMBL29279316 | 0.57 | ACHE (0.69) | NFKB1NFKB2RELAMEN1KMT2A | |
| SCHEMBL9226914 | 0.57 | CES1 (0.43) | MEN1KMT2ACES2CES1SETD7 | |
| Methyl Alcohol SCHEMBL28843164 | 0.56 | ESR1 (0.50) | CES2CES1 | |
| O-Xylene SCHEMBL2288470 | 0.55 | TSHR (0.83) | CES2CES1LMNA | |
| O-Xylene SCHEMBL21987916 | 0.55 | TSHR (0.83) | CES2CES1LMNA | |
| SCHEMBL67982 | 0.55 | CES1 (0.53) | MEN1KMT2ACES2CES1LMNA | |
| Biphenyl SCHEMBL28376025 | 0.54 | ALDH1A1 (0.60) | — | |
| SCHEMBL3461999 | 0.54 | NPC1 (0.44) | KMT2A | |
| SCHEMBL647841 | 0.54 | TDP1 (0.40) | NFKB1MEN1KMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759530-A1 | Triphenylamine derivative, and charge transport material and electrophotographic photoreceptor using the same | Takasago International Corporation (JP) | 2014-07-30 | — | — | EP | disclosed |