SCHEMBL15906349

SCHEMBL15906349

N#Cc1cc(I)c(NC(=O)c2cc(Cl)nn2-c2ncccc2Cl)c(C(N)=O)c1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
GRM4 Q14833 2/20 0.34
SLC2A1 P11166 2/20 0.34
SLC2A3 P11169 2/20 0.34
SLC2A4 P14672 2/20 0.34
SLC2A2 P11168 1/20 0.34
PPARG P37231 1/20 0.33
MALT1 Q9UDY8 1/20 0.33
NTRK1 P04629 1/20 0.33
PKM P14618 1/20 0.33
KDM4E B2RXH2 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DHODH Q02127 1/20 0.32
TRPV1 Q8NER1 2/20 0.32
GCK P35557 2/20 0.32
KCNH2 Q12809 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15906347 0.90 KMT2A (0.36) KMT2AGRM4PPARGMALT1PKM
SCHEMBL31060063 0.89 SLC2A1 (0.38) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL961226 0.89 SLC2A1 (0.38) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15906335 0.87 NTRK1 (0.40) KMT2AMALT1NTRK1
SCHEMBL31060056 0.84 SLC2A1 (0.37) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15906336 0.83 PKM (0.35) KMT2AGRM4SLC2A1SLC2A3SLC2A4
SCHEMBL13318550 0.82 SLC2A1 (0.37) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL959805 0.82 KMT2A (0.36) KMT2AGRM4PPARGMALT1NTRK1
SCHEMBL31059983 0.81 DHODH (0.42) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL29377007 0.81 DHODH (0.42) KMT2ASLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759200-A1 Active agent combinations with insecticide properties Bayer CropScience AG (DE) 2014-07-30 EP disclosed