SCHEMBL15907939

SCHEMBL15907939

O=S1(=O)c2cc(-c3ccccc3)ccc2-c2c1c1c(c3c2S(=O)(=O)c2cc(-c4ccccc4)ccc2-3)S(=O)(=O)c2cc(-c3ccccc3)ccc2-1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
APAF1 O14727 1/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
XBP1 P17861 1/20 0.43
PTBP1 P26599 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
GALK1 P51570 1/20 0.43
BLM P54132 1/20 0.43
SMAD3 P84022 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL903712 0.84 GPR3 (0.50) MEN1APAF1NPC1LMNAMAPT
SCHEMBL14353258 0.84 GPR3 (0.50) MEN1APAF1NPC1LMNAMAPT
SCHEMBL15907938 0.80 CYP11B1 (0.48) MEN1TDP2
SCHEMBL2622517 0.79 GPR3 (0.61) MEN1APAF1NPC1LMNAMAPT
SCHEMBL17444827 0.76 HPRT1 (0.45) MEN1APAF1NPC1LMNAMAPT
SCHEMBL10027505 0.75 MAOA (0.42) MEN1APAF1NPC1LMNAMAPT
SCHEMBL5798211 0.75 CHEK1 (0.62) MEN1APAF1NPC1LMNAMAPT
SCHEMBL25989992 0.75 ALDH1A1 (0.47) MEN1APAF1NPC1LMNAMAPT
SCHEMBL14174169 0.75 MAOA (0.47) MEN1APAF1NPC1LMNAMAPT
SCHEMBL25989968 0.75 ALDH1A1 (0.47) MEN1APAF1NPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140209867-A1 Sulfonyl Group-Contained Compound and Organic Electroluminescent Device Using Sulfonyl Group-Contained Compound and Preparation Method Thereof SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2014-07-31 US disclosed
US-20140209867-A1 Sulfonyl Group-Contained Compound and Organic Electroluminescent Device Using Sulfonyl Group-Contained Compound and Preparation Method Thereof SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2014-07-31 US disclosed