Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356754 | 0.91 | DGAT1 (0.36) | NAMPTNPC1RAB9ADGAT1CYP2A6 | |
| SCHEMBL16269898 | 0.87 | NPC1 (0.41) | NAMPTNPC1RAB9ADGAT1GAA | |
| SCHEMBL14904675 | 0.87 | GAA (0.35) | NAMPTNPC1RAB9ADGAT1CYP2A6 | |
| SCHEMBL15910403 | 0.83 | ELOVL1 (0.32) | — | |
| SCHEMBL16269900 | 0.81 | DGAT1 (0.41) | NAMPTNPC1RAB9ADGAT1GAA | |
| SCHEMBL15975600 | 0.81 | NPC1 (0.40) | NAMPTNPC1RAB9ADGAT1CYP2A6 | |
| SCHEMBL21021142 | 0.79 | CYP2A6 (0.42) | NPC1RAB9ACYP2A6CYP2E1GAA | |
| SCHEMBL15346873 | 0.78 | DGAT1 (0.39) | NPC1RAB9ADGAT1GAAALDH1A1 | |
| SCHEMBL2733010 | 0.78 | NPC1 (0.42) | NAMPTNPC1RAB9ACYP2A6CYP2E1 | |
| SCHEMBL15346451 | 0.77 | KMT2A (0.36) | NPC1RAB9ADGAT1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-20150166531-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318924-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NAMPT 2860/4885NPC1 3920/4885RAB9A 980/4885 |
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NAMPT 2860/4885NPC1 3920/4885RAB9A 980/4885 |
| US-20150166531-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | NAMPT 2860/4885NPC1 3920/4885RAB9A 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.