Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28042957 | 0.98 | TP53 (0.55) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL6029641 | 0.84 | HSD17B10 (0.55) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL28375786 | 0.83 | F7 (0.53) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL6030378 | 0.80 | HTT (0.58) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL14857135 | 0.80 | HTT (0.62) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL161322 | 0.79 | ALDH1A1 (0.59) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL31699264 | 0.79 | ALDH1A1 (0.59) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL12339307 | 0.79 | ALDH1A1 (0.50) | TP53TSHRHSD17B10USP2ALOX15 | |
| SCHEMBL93651 | 0.78 | ALDH1A1 (0.57) | TP53TSHRHSD17B10USP2ALOX15 | |
| Hydrochloric Acid SCHEMBL7835171 | 0.78 | ALDH1A1 (0.57) | TP53TSHRHSD17B10USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114258392-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| EP-2240449-B1 | NOVEL ANTI-INFECTIOUS DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES OF SAID DERIVATIVES IN TREATMENT | CENTRE NAT RECH SCIENT (FR) | 2016-01-06 | — | — | EP | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| EP-2948429-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014114742-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUÉES) DE ROUEN (FR) | 2014-07-31 | — | — | WO | disclosed |
| WO-2009108912-A1 | PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009101345-A1 | NOVEL ANTI-INFECTIOUS DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES OF SAID DERIVATIVES IN TREATMENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2009-08-20 | — | — | WO | disclosed |
| US-20090036685-A1 | Process for Producing Imidazothiazole Derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1908766-A1 | PROCESS FOR PRODUCTION OF IMIDAZOTHIAZOLE DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |
| US-20080015179-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2008-01-17 | — | — | US | disclosed |
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | PURDUE RESEARCH FOUNDATION | 2003-02-13 | — | — | US | disclosed |
| WO-2002030466-A2 | PHARMACEUTICAL APPLICATIONS OF HYDROTROPIC AGENTS, POLYMERS THEREOF, AND HYDROGELS THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2002-04-18 | — | — | WO | disclosed |
| EP-0347831-B1 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-4971964-A | INHIBITORS OF THROMBOXANE SYNTHASE, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORU AGENTS, CANCER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0347831-A2 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | CBR3, CBR1, CYB5R3 | TP53 3341/4885TSHR 517/4885HSD17B10 983/4885 |
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | HMGB2, HTT, ABCG2 | TP53 350/4885TSHR 3523/4885HSD17B10 3334/4885 |
| US-20080015179-A1 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | TP53 4383/4885TSHR 131/4885HSD17B10 2647/4885 |
| US-20090036685-A1 | Process for Producing Imidazothiazole Derivatives | NAMPT, NAPRT, NNT | TP53 4881/4885TSHR 4194/4885HSD17B10 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.