Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1591435 | 0.83 | TP53 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Hydrochloric Acid SCHEMBL28042957 | 0.81 | TP53 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL6029641 | 0.81 | HSD17B10 (0.55) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL4002015 | 0.81 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL6227030 | 0.80 | F7 (0.62) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL4000774 | 0.79 | KDM4E (0.47) | ALDH1A1TP53TSHRHSD17B10HTT | |
| SCHEMBL4667859 | 0.78 | TRPM8 (0.47) | ALDH1A1TP53TSHRHSD17B10NPSR1 | |
| SCHEMBL14857135 | 0.78 | HTT (0.62) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL6030378 | 0.78 | HTT (0.58) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL161322 | 0.77 | ALDH1A1 (0.59) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655247-A | Enhancing T cell function and treating T cell dysfunction disorders with a combination of a LSD inhibitor and a PD1 binding antagonist | 艾比克斯治疗私人有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-111655247-A | Enhancing T cell function and treating T cell dysfunction disorders with a combination of a LSD inhibitor and a PD1 binding antagonist | 艾比克斯治疗私人有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110770221-A | Methods for improving memory and cognition and for treating memory and cognitive disorders | 卡维昂公司 | 2020-02-07 | — | — | CN | disclosed |