SCHEMBL15914974

SCHEMBL15914974

c1ccc([SiH](c2ccccc2)C2CCCCC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.36
HPGD P15428 3/20 0.34
IDO1 P14902 2/20 0.34
POLB P06746 1/20 0.34
SLC18A3 Q16572 1/20 0.34
G6PC1 P35575 1/20 0.34
ALDH1A1 P00352 3/20 0.33
EPHX1 P07099 1/20 0.33
GAA P10253 1/20 0.33
USP2 O75604 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15186488 0.98 POLB (0.35) EPHX2POLBSLC18A3G6PC1ALDH1A1
SCHEMBL24305874 0.88 AGER (0.39) POLBALDH1A1EPHX1NPC1RAB9A
SCHEMBL18860237 0.87 HRH3 (0.32) SLC18A3NOS1NOS2SIGMAR1
SCHEMBL561158 0.81 EPHX2 (0.36) EPHX2HPGDIDO1POLBSLC18A3
SCHEMBL15914932 0.78 POLB (0.35) EPHX2POLBSLC18A3G6PC1ALDH1A1
SCHEMBL27871054 0.77 HPGD (0.35) EPHX2HPGDIDO1POLBSLC18A3
SCHEMBL15915460 0.76 IDO1 (0.35) EPHX2HPGDIDO1POLBSLC18A3
SCHEMBL20146336 0.76 IDH1 (0.33) GAATAAR1
SCHEMBL15915709 0.73 IDO1 (0.32) EPHX2IDO1POLBALDH1A1GAA
SCHEMBL27614195 0.73 GAA (0.34) EPHX2HPGDIDO1ALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027090-A Method for generating silanol by oxidizing silane 吉林大学 2024-05-14 CN disclosed
CN-114207901-B Nonaqueous electrolyte solution and nonaqueous electrolyte battery 三菱化学株式会社 2024-04-09 CN disclosed
EP-3848992-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-04-19 EP disclosed
CN-112387313-B Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2022-08-16 CN disclosed
CN-112387313-A Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2021-02-23 CN disclosed
US-9970103-B2 Film deposition material, sealing film using the same and use thereof TOSOH CORPORATION (JP) 2018-05-15 US disclosed
CN-103781937-B Filmogen, the diaphragm seal using the filmogen, and application thereof 东曹株式会社 2017-05-31 CN disclosed
US-20160326642-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2016-11-10 US disclosed
US-20140219903-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2014-08-07 US disclosed
CN-103781937-A Film-forming material, sealing film using same, and use of sealing film TOSOH CORP 2014-05-07 CN disclosed