Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921913 | 0.82 | KDM4E (0.61) | ALDH1A1HPGDMAPK1TDP1MAPT | |
| SCHEMBL15919336 | 0.76 | ALDH1A1 (0.76) | ALDH1A1HPGDMAPK1NOTUMMAPT | |
| SCHEMBL28199327 | 0.73 | NPC1 (0.62) | ALDH1A1HPGDLMNARAB9ANPC1 | |
| SCHEMBL15919335 | 0.72 | NOTUM (0.71) | ALDH1A1HPGDNOTUMMAPTLMNA | |
| SCHEMBL15919341 | 0.72 | NOTUM (0.67) | ALDH1A1HPGDTDP1NOTUMMAPT | |
| SCHEMBL4638678 | 0.69 | NOTUM (0.60) | ALDH1A1HPGDMAPK1TDP1NOTUM | |
| SCHEMBL21354520 | 0.68 | GAA (0.56) | ALDH1A1HPGDMAPK1MAPTLMNA | |
| SCHEMBL21354434 | 0.68 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTLMNAHTT | |
| SCHEMBL5004887 | 0.68 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPK1TDP1NOTUM | |
| SCHEMBL28674639 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116228-A1 | USP14 INHIBITORS FOR TREATING OR PREVENTING VIRAL INFECTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | WO | disclosed |