Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355793 | 0.87 | NOTUM (0.69) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL15919341 | 0.85 | NOTUM (0.67) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL6923018 | 0.81 | SMN1; SMN2 (0.73) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL15919336 | 0.77 | ALDH1A1 (0.76) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL18356164 | 0.75 | NOTUM (0.72) | NOTUMALDH1A1RAB9ALMNAGAA | |
| SCHEMBL15919337 | 0.75 | ALDH1A1 (0.61) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL14226118 | 0.74 | ALDH1A1 (0.71) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL14226116 | 0.73 | ALDH1A1 (0.70) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL15919339 | 0.72 | ALDH1A1 (0.54) | NOTUMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL18356313 | 0.72 | ALDH1A1 (0.65) | NOTUMALDH1A1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116228-A1 | USP14 INHIBITORS FOR TREATING OR PREVENTING VIRAL INFECTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | WO | disclosed |