Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 8/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | HTT | P42858 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | MITF | O75030 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 12/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749691 | 0.86 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL15919341 | 0.85 | NOTUM (0.67) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL1981311 | 0.82 | NOTUM (0.74) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL6922668 | 0.81 | SMN1; SMN2 (0.76) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL17949730 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL17949728 | 0.80 | SMN1; SMN2 (0.78) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL15919337 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL15919335 | 0.77 | NOTUM (0.71) | ALDH1A1MAPTHTTRAB9ALMNA | |
| SCHEMBL17949729 | 0.77 | SMN1; SMN2 (0.76) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL15919339 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116228-A1 | USP14 INHIBITORS FOR TREATING OR PREVENTING VIRAL INFECTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | WO | disclosed |