Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919743 | 0.91 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1HPGDFKBP1AUSP2 | |
| Hydrochloric Acid SCHEMBL15905480 | 0.90 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1HPGDFKBP1AUSP2 | |
| SCHEMBL15919450 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1HPGDFKBP1AUSP2 | |
| SCHEMBL15919672 | 0.87 | MAPT (0.47) | L3MBTL1ALDH1A1HPGDUSP2KDM4E | |
| SCHEMBL15919356 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4EPOLBMEN1 | |
| SCHEMBL15904995 | 0.78 | MAPT (0.50) | L3MBTL1ALDH1A1HPGDUSP2KDM4E | |
| Hydrochloric Acid SCHEMBL15905149 | 0.77 | MAPT (0.49) | L3MBTL1ALDH1A1HPGDUSP2KDM4E | |
| SCHEMBL15919659 | 0.76 | KDM4E (0.44) | L3MBTL1ALDH1A1HPGDUSP2KDM4E | |
| SCHEMBL17327539 | 0.76 | KMT2A (0.44) | ALDH1A1HPGDHTTKDM4EPOLB | |
| SCHEMBL15905383 | 0.76 | MAPT (0.57) | ALDH1A1HPGDUSP2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | L3MBTL1 1568/4885ALDH1A1 289/4885HPGD 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.