Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL2791988 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL28201145 | 0.98 | ALDH1A1 (0.81) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL27750922 | 0.95 | ALDH1A1 (0.94) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL9684173 | 0.92 | ALDH1A1 (0.90) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL7208557 | 0.92 | ALDH1A1 (0.90) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL29822171 | 0.92 | ALDH1A1 (1.00) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL29349552 | 0.92 | ALDH1A1 (1.00) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL32661377 | 0.92 | ALDH1A1 (1.00) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL2774 | 0.92 | ALDH1A1 (1.00) | ALDH1A1CASP1MEN1KMT2ACASP7 | |
| Quinoline SCHEMBL1270969 | 0.92 | ALDH1A1 (1.00) | ALDH1A1CASP1MEN1KMT2ACASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610327-A | With the active substd quinolines first alcohol compound of reversing tumor cells resistance and its synthetic method and application | 河南师范大学 | 2018-10-02 | — | — | CN | claimed |
| CN-108452304-A | The preparation method of conversion composite nano materials and product and application on rare earth | 浙江大学 | 2018-08-28 | — | — | CN | claimed |
| CN-104829439-B | A kind of (Z, Z, E) -7, the synthetic method of 11,13- ten six three olefine aldehydrs of carbon | 宁波纽康生物技术有限公司 | 2018-06-12 | — | — | CN | claimed |
| CN-104840961-B | Cancer stem cell sensitive agent is preparing the application in anticancer stem cell test kit | MA LIWEI (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-104840961-A | Application of cancer stem cell sensitive agent in preparation of anti-cancer stem cell kit | MA LIWEI | 2015-08-19 | — | — | CN | claimed |
| CN-103053549-A | Photoactivated solenopsis invicta insecticide | UNIV SOUTH CHINA AGRICULT | 2013-04-24 | — | — | CN | claimed |
| US-20110092488-A1 | Quninoline Methanol Compounds for the Treatment and Prevention of Parasitic Infections | DOW GEOFFREY | 2011-04-21 | — | — | US | claimed |
| WO-2010144101-A1 | NEXT GENERATION QUINOLOINE METHANOLS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF U.S. (US) | 2010-12-16 | — | — | WO | claimed |
| WO-2010144102-A1 | PENTAFLUOROSULFANYL ANALOGS OF MEFLOQUINE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2010-12-16 | — | — | WO | claimed |
| WO-2008060269-A2 | QUINOLINE METHANOL COMPOUNDS FOR THE TREATMENT AND PREVENTION OF PARASITIC INFECTIONS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2008-05-22 | — | — | WO | claimed |
| CN-1316279-A | X-ray magnetic therapy machine for PDT therapy of cancer by combining radiatherapy with chemicotherapy and its medicine | DONG SEN (CN) | 2001-10-10 | — | — | CN | claimed |
| US-4076537-A | Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | claimed |
| JP-56086182-A | — | — | None | — | — | JP | disclosed |
| CN-119869610-A | Preparation method of catalyst and preparation method of ethyl orthosilicate | 华陆工程科技有限责任公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119223695-A | Method and device for trapping nicotine in flue gas | 中国烟草总公司郑州烟草研究院 | 2024-12-31 | — | — | CN | disclosed |
| CN-108383780-B | Refining method of pitavastatin (III) | 湖北荆江源制药股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-0107938-A1 | Quinoline or hydroquinoline compounds, their preparation and pharmaceutical compostions comprising them | KOWA COMPANY, LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| WO-1983003970-A1 | COMPOUNDS, COMPOSITIONS AND METHOD OF TREATMENT FOR IMPROVING CIRCULATORY PERFORMANCE | MAROKO PETER R | 1983-11-24 | — | — | WO | disclosed |
| JP-S5686182-A | IMIDAZOLYLETHOXY DERIVATIVE OF QUINOLINE METHANOL | SQUIBB & SONS INC | 1981-07-13 | — | — | JP | disclosed |
| US-4076537-A | Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092488-A1 | Quninoline Methanol Compounds for the Treatment and Prevention of Parasitic Infections | MTX1, MTX2, NQO2 | ALDH1A1 1313/4885CASP1 274/4885MEN1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.