Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119792 | 0.86 | ALDH1A1 (0.82) | LMNAMAPTGAAL3MBTL1KMT2A | |
| SCHEMBL15919628 | 0.85 | NPY2R (0.68) | LMNAMAPTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7457778 | 0.82 | LMNA (0.66) | LMNAMAPTGAAL3MBTL1KMT2A | |
| SCHEMBL15919634 | 0.81 | KDM4E (0.66) | MAPTGAAALDH1A1CYP2C19NPSR1 | |
| SCHEMBL7312797 | 0.79 | CYP1A2 (0.67) | LMNAMAPTGAAL3MBTL1KMT2A | |
| SCHEMBL11179944 | 0.79 | ALDH1A1 (0.96) | LMNAMAPTKMT2AALDH1A1PKM | |
| SCHEMBL3801054 | 0.78 | SPR (0.50) | MAPTALDH1A1KDM4E | |
| SCHEMBL13902470 | 0.78 | ALDH1A1 (0.70) | LMNAMAPTGAAL3MBTL1KMT2A | |
| SCHEMBL1651693 | 0.78 | ALDH1A1 (1.00) | LMNAMAPTKMT2AALDH1A1PKM | |
| SCHEMBL14066248 | 0.77 | LMNA (0.73) | LMNAMAPTGAAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |