Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ME2 | P23368 | 1/20 | 0.56 |
| ▸ | ME1 | P48163 | 1/20 | 0.56 |
| ▸ | ME3 | Q16798 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919651 | 0.92 | FAAH (0.65) | KDM4EFAAHALDH1A1NPC1TP53 | |
| SCHEMBL15919636 | 0.88 | FAAH (0.67) | KDM4EFAAHALDH1A1NPC1TP53 | |
| SCHEMBL15919638 | 0.88 | MAPT (0.70) | FAAHALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL2897923 | 0.86 | KDM4E (0.77) | KDM4EFAAHALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL10729724 | 0.86 | KDM4E (0.77) | KDM4EFAAHALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL15920276 | 0.85 | MAPT (0.70) | KDM4EFAAHALDH1A1NPC1RAB9A | |
| SCHEMBL3801054 | 0.85 | SPR (0.50) | KDM4EALDH1A1NPC1TP53RAB9A | |
| SCHEMBL7096012 | 0.83 | KDM4E (0.69) | KDM4EFAAHALDH1A1NPC1TP53 | |
| SCHEMBL7465143 | 0.82 | KDM4E (0.51) | KDM4EMAPT | |
| SCHEMBL7465149 | 0.82 | KDM4E (0.72) | KDM4EFAAHALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |