Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919634 | 0.92 | KDM4E (0.66) | FAAHPOLBNPC1RAB9ATP53 | |
| SCHEMBL15919638 | 0.86 | MAPT (0.70) | FAAHSMN1; SMN2GAAPAK1ALDH1A1 | |
| SCHEMBL15919636 | 0.83 | FAAH (0.67) | FAAHPOLBNPC1RAB9ATP53 | |
| SCHEMBL15920276 | 0.83 | MAPT (0.70) | FAAHPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4693278 | 0.83 | MAPT (0.51) | FAAHPOLBALOX15TSHRNPC1 | |
| SCHEMBL27652942 | 0.82 | NPC1 (0.83) | FAAHPOLBTSHRNPC1RAB9A | |
| SCHEMBL28604386 | 0.82 | KCNA5 (0.60) | POLBNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL23486325 | 0.80 | TSHR (0.76) | FAAHPOLBALOX15TSHRNPC1 | |
| SCHEMBL12994636 | 0.80 | TSHR (0.71) | FAAHPOLBALOX15TSHRNPC1 | |
| SCHEMBL23486322 | 0.80 | TSHR (0.71) | FAAHPOLBALOX15TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |