Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14205955 | 0.89 | MEN1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL3302462 | 0.86 | LMNA (0.70) | KCNA5ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1181426 | 0.83 | DRD4 (0.55) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL3301180 | 0.83 | LMNA (0.68) | KCNA5ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3309762 | 0.82 | MAPT (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL6893687 | 0.82 | ALDH1A1 (0.79) | KCNA5ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15919651 | 0.82 | FAAH (0.65) | ALDH1A1SMN1; SMN2KMT2ANPC1TP53 | |
| SCHEMBL13118219 | 0.81 | KCNT1 (0.76) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL18843660 | 0.81 | ALDH1A1 (0.68) | KCNA5ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL18843662 | 0.81 | ALDH1A1 (0.68) | KCNA5ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214140-B | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113214139-B | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113214140-A | Piperidine amide derivative, pharmaceutical composition and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113214139-A | Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof | 江苏谛奇医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |