Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920206 | 0.81 | NPY2R (0.70) | NPY2RGAAEDNRBEDNRAALDH1A1 | |
| SCHEMBL21587771 | 0.69 | NPY2R (0.41) | NPY2RGAAKMT2APTGS2ALDH1A1 | |
| SCHEMBL2628017 | 0.65 | GAA (0.56) | NPY2RGAAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21587812 | 0.65 | NPY2R (0.37) | NPY2RKMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL23720154 | 0.65 | HTR6 (0.48) | NPY2RALDH1A1CYP2C19TDP1HSD17B10 | |
| SCHEMBL2628020 | 0.64 | GAA (0.65) | NPY2RGAAATMKMT2AALDH1A1 | |
| SCHEMBL28585199 | 0.64 | MAOA (0.42) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL28890915 | 0.64 | NPY2R (0.38) | NPY2RGAAKMT2APTGS2ALDH1A1 | |
| SCHEMBL3884476 | 0.63 | CYP2C19 (0.42) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL8119090 | 0.63 | PKM (0.53) | KMT2APTGS2ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |