Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479258 | 0.80 | ALDH1A1 (0.47) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL7547404 | 0.80 | HTR6 (0.48) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL29827353 | 0.79 | NPY2R (0.38) | HTR6CYP2C19NPY2RCA1CA2 | |
| SCHEMBL28414975 | 0.79 | LMNA (0.56) | ALDH1A1HSD17B10TDP1TSHRSMN1; SMN2 | |
| SCHEMBL28891448 | 0.78 | NPY2R (0.46) | HTR6CYP2C19NPY2RALDH1A1TDP1 | |
| SCHEMBL28335740 | 0.78 | HTR6 (0.49) | HTR6NPY2RCA1CA2ALDH1A1 | |
| SCHEMBL11848869 | 0.76 | HTR6 (0.44) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL9197961 | 0.76 | HTR6 (0.44) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL7637220 | 0.76 | GBA1 (0.47) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL780336 | 0.76 | CYP2C19 (0.52) | HTR6CYP2C19ALDH1A1TSHRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
| CN-110511166-A | A kind of synthetic method of two arylmethyls alkyl sulfone | UNIV CHENGDU TECHNOLOGY | 2019-11-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | HTR6 3570/4885CYP2C19 346/4885NPY2R 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.